产品货号：
Z14901
中文名称：
FAM175A/ABRAXAS1抗体
英文名称：
Anti-FAM175A/ABRAXAS1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FAM175A/ABRAXAS1 Antibody |
| 指标别名 | ABRA1;CCDC98;FAM175A;Protein FAM175A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | ABRAXAS1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CCDC98 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human CCDC98.The immunogen is located within amino acids 80 - 130 of CCDC98. |
| 计算分子量 | 47kDa |
| 成分 | CCDC98 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CCDC98 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | CCDC98,also known as Abraxas 1,was identified through protein binding studies using the breast and ovarian predisposition protein BRCA1 as the binding target.CCDC98 recruits RAP80,a ubiquitin-binding protein,to BRCA1,allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation.Both CCDC98 and RAP80 are required for DNA damage resistance,G2-M checkpoint control,and DNA repair.Cells depleted of either CCDC98 or RAP80 exhibited increased sensitivity to ionizing radiation,although not as much as in BRCA1-depleted cells,suggesting that CCDC98 and RAP80 control only part of the DNA damage response role of BRCA1.At least two isoforms of CCDC98 are known to exist. |
| Uniprot ID | Q6UWZ7 |
| 基因名全称 | Family with sequence similarity 175,member A |
| 蛋白名全称 | Family with sequence similarity 175,member A |
| 推荐稀释比 | CCDC98 antibody can be used for detection of CCDC98 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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